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According to a Mackay Level I model calculation, the main target compartment for trans-N1,N1,N4,N4-tetrakis(2-hydroxyethyl)-1,4-cyclohexanedicarboxamide will be the hydrosphere (99.999 %). The calculated Henry’s Law constant of 0.0000006 Pa m³/mol at 20 °C indicates very low volatility of trans-N1,N1,N4,N4-tetrakis(2-hydroxyethyl)-1,4-cyclohexanedicarboxamide from surface waters. With a Koc of 0.5 l/kg, there is no relevant sorption potential of the substance to soil or sediment organic matter (Blume scale).


The QSAR calculated rate constant for the OH sensitized photodegradation of N1,N1,N4,N4-tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide is approximately 87.8E-12 cm3/(molecule * s). At 500,000 OH radicals / cm3 (typical for central Europe), this corresponds to a half-life of 4.4 hours (24 hour-days). Hydrolysis is very slow under environmental conditions. While no ready biodegradation was observed in a manometric respirometry test, degradation rates up to 20% indicate a potential for biodegradation, which is expected to be the predominant way of removal from the environment. The partition coefficient 1-octanol/water was determined as log Kow = -1.32 at 20.6 °C, indicating negligible potential for bioaccumulation.