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EC number: 700-597-4
CAS number: 1215841-86-3
The acute toxicity of trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide was examined. After oral application the LD50 for rats was found to be > 2000 mg/kg bw. The acute inhalation LC50 for rats was found to be > 5.07 mg/L .
Studies in Animals:
After oral application the LD50for rats was found to be
> 2000 mg/kg bw in a test performed according to OECD Guideline 423. No
signs of toxicity were observed. No
animal died prematurely.
After exposition via inhalation (dust) the LC50 for
rats was found to be > 5.07 mg/L bw in a test performed according to
OECD Guideline 403. The animals showed slight ataxia and slight
dyspnoea. No animal died prematurely. No pathological findings were
noted at necropsy. One of the 3 female animals appeared to be reduced in
body weight gain.
According to the criteria of EC Directive 67/548/EEC and EC
Regulation 1272/2008 and subsequent regulations on classification,
labelling and packaging of substances and mixtures and based on the
results of the studies
is not classified.
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