Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 700-597-4 | CAS number: 1215841-86-3
Endpoint summary
Administrative data
Description of key information
The acute toxicity of trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide was examined. After oral application the LD50 for rats was found to be > 2000 mg/kg bw. The acute inhalation LC50 for rats was found to be > 5.07 mg/L .
Key value for chemical safety assessment
Additional information
Studies in Animals:
Oral
After oral application the LD50for rats was found to be > 2000 mg/kg bw in a test performed according to OECD Guideline 423. No signs of toxicity were observed. No animal died prematurely.
Inhalation:
After exposition via inhalation (dust) the LC50 for rats was found to be > 5.07 mg/L bw in a test performed according to OECD Guideline 403. The animals showed slight ataxia and slight dyspnoea. No animal died prematurely. No pathological findings were noted at necropsy. One of the 3 female animals appeared to be reduced in body weight gain.
Justification for classification or non-classification
According to the criteria of EC Directive 67/548/EEC and EC Regulation 1272/2008 and subsequent regulations on classification, labelling and packaging of substances and mixtures and based on the results of the studies trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide is not classified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
