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EC number: 701-218-5
CAS number: -
acute oral toxicity, rat: LD50 > 2000 mg/kg bw
acute dermal toxicity, rat: LD50 > 2000 mg/kg bw
An acute oral toxicity study according OECD TG 423 was performed on 3
(initial testing) plus 3 (repeat) female rats, receiving each a single
dose of 2000 mg/kg of the test item formulated in polyethylene glycol.
No mortalities, no clinical signs, no effects on body weigth gain and no
gross pathological findings were observed. The LD50 of the test material
was estimated from the flow chart of the OECD TG 423, Annex 2d, to be
>/= 5000 mg/kg bw.
An acute dermal toxicity study was performed according to OECD TG 402.
For the purpose of a limit test 2000 mg/kg of the test item was applied
semiocclusive on 5 male and 5 female rats for 24 hours. No mortalities,
no clinical signs, no effects on weight development and no gross
pathological findings were observed during the 14 -days observation
period. The resulting LD50 was therefore > 2000 mg/kg bw for both sexes
An Acute Oral Toxicity study according to OECD 423 conducted on female
rats revealed no mortalities, no clinical signs and no effects on body
weight gain up to the limit dose of 2000 mg/kg bw. At necropsy no gross
pathological findings were observed. The LD50 was estimated from the
flow chart of the OECD TG 423, Annex 2d, to be >/= 5000 mg/kg bw.
No study on acute inhalation toxicity is available for the substance.
An Acute Dermal Toxicity study according to OECD TG 402 with a limit
dose of 2000 mg/kg, applied semiocclusive on the skin of 5 male and 5
female rats for 24 hours, also revealed no mortalities, no clinical
signs, no effects on body weight development and no gross pathological
findings. The resulting LD50 was therefore > 2000 mg/kg bw for both
No classification required for acute toxicity according to Regulation
(EC) No 1272/2008, Annex I.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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