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EC number: 252-552-9
CAS number: 35415-27-1
The test material 1,2,4-benzenetricarboxylic acid, trioctyl ester was
tested for acute oral toxicity (RL2, according to OECD TG
401, GLP conform study). In this limit test 5 male and 5 female
Sprague-Dawley rats were exposed to the limit dose of 2000 mg/kg
bodyweight. Acontrol group received only vehicle (corn oil). Animals
were checked for mortality, clinical signs and body weight changes
during the 14 days observation period. At the end of the study animals
were sacrificed and necropsy was performed. No mortality, relevant
clinical signs or differnec in between body weight development between
control and treatment group were observed. Based on the results
obtained, the LD50 was judged to be > 2000 mg/kg bodyweight in
These findings are supported by another study
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