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EC number: 252-552-9
CAS number: 35415-27-1
The study used as source investigated acute toxicity to fish (Oryzias
latipes) during 96 hours of exposure according to OECD 203 and in
compliance with GLP. The 96h-LC50 (Oryzias latipes, mortality) was
determined to be >108 mg/L (corrected for the molecular weight of the
target substance). The validity criteria of the test guideline were
fulfilled and results of the source compound were considered applicable
to the target compound. Justification and applicability of the
read-across approach (structural analogue) is outlined in the
read-across report in section 13 or find a link in cross-reference
No acute toxicity data on fish for the submission substance is available. However adequate and reliable data for structural analogues is available (i.e. C8TM and C8C10TM, for read-across justification please see read-across report in section 13). The derived 96h-LC50 (Oryzias latipes, mortality) was >108 mg/L (corrected for the molecular weight of the target substance).
No acute aquatic toxicity data for the submission substance is
available. However adequate and reliable data for structural analogues
(i.e. C8TM and C8C10TM, for read-across justification please see
read-across report in section 13) are reported below.
In a reliable acute toxicity study on fish (according to OECD 203 and in
compliance with GLP, MoE Japan, 2001, RL2) no mortality was observed in
a limit test at 100 mg/L test substance (analogue substance: trioctyl
benzene-1,2,4-tricarboxylate, trioctyl ester, C8TM, CAS no. 89-04-3;
corresponding to 108 mg/L of the target substance). Furthermore, no
mortality was observed in the supporting study (EU Method C.1, GLP,
Huels AG, 1994, RL2) in a limit test at 3 mg/L test substance (analogue
substance: 1,2,4 -benzenetricarboxylic acid, mixed decyl and octyl
triesters, C8C10TM, CAS no. 90218-76-1; corresponding to 3 mg/L of the
target substance). In conclusion, no acute toxicity to fish is expected
below the water solubility of the submission substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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