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EC number: 252-552-9
CAS number: 35415-27-1
No chronic toxicity data on aquatic invertebrates for the submission substance is available. However adequate and reliable data for structural analogues is available (i.e. C8TM and C8C10TM, for read-across justification please see read-across report in section 13). The derived 21d-NOEC (Daphnia magna, reproduction) = 4.4 mg/L (corrected for the molecular weight of the target substance).
No chronic aquatic toxicity data for the submission substance is
available. However adequate and reliable data for structural analogues
(i.e. C8TM and C8C10TM, for read-across justification please see
read-across report in section 13) are reported below.
In a reliable long-term toxicity study on daphnids (according to OECD
211 and in compliance with GLP, MoE Japan, 2001, RL1), significant
effects on lethality of parent daphnids and reproduction were observed
during 21 days of exposure (analogue substance: trioctyl
benzene-1,2,4-tricarboxylate, trioctyl ester, C8TM, CAS no. 89-04-3)
only at concentrations well above
the water solubility limit. All tested concentrations lay
above the water solubility of the test substance (solubilizer was used).
No significant adverse effects were observed in concentrations up to
4.04 mg/L (corresponding to 4.4 mg/L of the target substance), and in
the limit test of the supporting study at 4.5 mg/L (OECD 211, GLP, Huels
AG, 1997, RL2; analogue substance: 1,2,4-benzenetricarboxylic acid,
mixed decyl and octyl triesters, C8C10TM, CAS no. 90218-76-1;
corresponding to 4.2 -4.9 mg/L of the target substance). In conclusion,
no long-term toxicity to daphnia is expected below the water solubility
of the analogue and submission substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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