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EC number: 923-725-2
CAS number: -
biodegradability of Biofert Plusz was investigated in a study conducted
according to OECD Guideline 301 B over a period of 28 days and using
non-adapted activated sludge as inoculum source. The biodegradation rate
was determined by measurement of CO2 evolution. Inoculum blank,
procedural/functional control with the reference substance sodium
benzoate, and toxicity control using 80 mg/L test material and 20 mg/L
reference compound were performed. Biofert Plusz proved to
be readily biodegradable and
fulfilling the 10-d window criterion (92% biodegradation after 28 d).
The functional control reached the pass level >60% after 14 d. In the
toxicity control containing both test and reference substance 81% biodegradation
based on ThCO2 occurred within 14 d thus indicating that the test item
was not inhibitory
at the concentration tested.
Experimentally derived values on hydrolysis and photooxidation of
Biofert are not available. In Annex VIII of Regulation (EC) No
1907/2006, it is laid down that further degradation testing shall be
considered if the chemical safety assessment according to Annex I
indicates the need to investigate further the degradation of the
substance. According to reliable study results, Biofert Plusz is
considered to be rapidly biodegraded in the environment and the
bioaccumulation potential is regarded to be insignificant. Therefore,
the performance of experimental studies on hydrolysis or
photodegradation are assumed to be scientifically not justified.
Henry's Law constant of L-threonine as the main constituent of Biofert
plusz was calculated using EPIWIN (v4.0), HENRYWIN (v3.20). The
calculation of Henry's Law constant according to the equation H=vp/ws
yielded a value of 7.34E-009 Pa x m3/mole using an estimated water
solubility of 2.79e+005 mg/l and a vapour pressure of 7.88E-009 mm Hg.
Based on the result, threonine can be considered as practically
non-volatile from aqueous solution.
Experimental studies on adsorption/desorption of Biofert are not
According to REACH Regulation (Annex VIII, 9.3.1, column II), a study on
adsorption/desorption does not need to be done if the the test material
is readily biodegradable.
For the bioaccumulation of Biofert Plusz no experimental studies were
identified. Biofert Plusz is a complex mixture containing organic and
inorganic components (UVCB-substance). L-threonine is the main component
of Biofert Plusz. Therefore the bioaccumulation factor of L-Threonine
was calculated via EPIWIN v4.0, BCFBAF v3.00. The calculation yielded a
BCF=3.162 L/kg ww demonstrating that the substance exhibits no
significant bioaccumulation potential.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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