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EC number: 923-725-2
CAS number: -
A local lymph node assay with Biofert Plusz was performed according to
OECD Guideline 429 (adopted in 2002). The test item was suspended in
propylene glycol at concentrations of 25, 50 and 100% of the original
liquid substance (7.03, 14.05, or 28.1 dry mass respectively). The
animals did not show any clinical signs or influence on body weight.
The proliferative capacity of pooled lymph nodes was determined by the
incorporation of 3H-methyl thymidine. A test item is regarded as a
sensitiser if the exposure resulted in a 3 -fold or greater increase in
incorporation of 3H-methyl thymidine as compared to the ontrol (as
indicated by the stimulation index).
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