Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 246-467-6 | CAS number: 24801-88-5
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 2012-07-26 to 2012-08-01
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- 27 July 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Version / remarks:
- 30 May 2008
- Deviations:
- no
- GLP compliance:
- no
- Other quality assurance:
- ISO/IEC 17025 (General requirements for the competence of testing and calibration laboratories)
- Type of method:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- < -20 °C
- Atm. press.:
- 1 013 hPa
- Remarks on result:
- other: No melting point was found between -150 and +50°C under these conditions. A glass transition was observed at -143°C.
- Conclusions:
- No melting point was found between -150 and +50°C under the conditions of the study. A glass transition was observed at -143°C. The result is considered to be reliable.
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 2013-11-13 to 2013-11-14
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- The study was conducted in accordance with OECD 102 but not in compliance with relevant quality management system.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.1 (Melting / Freezing Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- 1995
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 113 (1981) Screening test for thermal stability and stability in air
- Version / remarks:
- 1981
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- thermal analysis
- Remarks:
- Differential Scanning Calorimeter
- Key result
- Melting / freezing pt.:
- < -100 °C
- Atm. press.:
- 1 013 hPa
- Remarks on result:
- other: Test item has no melting point above -100°C
- Conclusions:
- The melting point of the substance was determined not to be above -100°C at 1013 hPa using a relevant test method. The result is considered to be reliable.
Referenceopen allclose all
The DSC measurements were performed twice. After cooling to -150°C at a rate of 2 K/min the sample was heated to 50°C at a rate of 5 K/min. The cooling as well as the heating curve show only a glass transition, indicating that the test item had solidified amorphously. The DSC thermograms are attached.
No other thermal effect from crystallisation or melting was registered upon further heating.
Thermal stability (DSC measurement):
DSC measurement in a closed glass crucible showed an inconclusive base line. The DSC thermogram attached (figure 1).
Melting point/melting range (DSC measurement):
Two DSC measurements in aluminium crucibles with a hole showed no thermal effects in the temperature range of -100°C to room temperature. Therefore, the test item has no melting point above -100°C. The DSC thermograms attached (figure 2).
Description of key information
Melting point: <-1000°C at 1013 hPa (OECD 102)
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -100 °C
Additional information
Two measured melting/freezing point studies are available for the registered substance. In Mekelburger 2012, a glass transition temperature of -143°C at 1013 hPa was determined for the substance in accordance with OECD Test Guideline 102 (DSC - Differential Scanning Calorimetry) and in compliance with a known quality system (ISO 17025). Similarly, in Ahrens 2013, the result of thermal stability testing using DSC, indicates the test item has no melting point above -100°C (i.e. <-100°C) at 1013 hPa. The results were considered to be reliable and are used as weight of evidence.
In a secondary source to which reliability could not be assigned, a melting point of <0°C was reported for the substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
