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EC number: 246-467-6
CAS number: 24801-88-5
Table 1. Test results
Nominal concentration (ppm)
Survival of parental daphnia (%)
Total young produced +/-Stand Dev
Young produced per female +/-Stand Dev
Initial survival of offspring (%)
(21-day) NOEC: ≥1 ppm survival and
reproduction, Daphnia magna, read across from
N-(3-(trimethoxysilyl)propyl)ethylenediamine (CAS 1760-24-3).
There are no reliable long-term
invertebrate toxicity data available for
triethoxy(3-isocyanatopropyl)silane (CAS 24801-88-5), therefore good
quality data for an appropriate structural analogue,
N-(3-(trimethoxysilyl)propyl)ethylenediamine (CAS 1760-24-3), have been
Both substances rapidly hydrolyse
to structurally similar hydrolysis products, 3-aminopropylsilanetriol
and N-(3-(trihydroxysilyl)propyl)ethylenediamine, respectively. The
other hydrolysis products are ethanol and methanol, respectively, and
are not considered likely to contribute to effects observed in studies.
A 21-day NOEC of ≥1 ppm (≥1 mg/l)
has been determined for the effects of
N-(3-(trimethoxysilyl)propyl)ethylenediamine (CAS 1760-24-3) on survival
and reproduction of Daphnia magna. The results are expressed
relative to nominal concentrations of the test substance. However the
substance is subject to rapid hydrolysis and under the test conditions
it is therefore likely that exposure will have been to its hydrolysis
products (methanol and N-(3-(trihydroxysilyl)propyl)ethylenediamine).
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