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EC number: 229-722-6
CAS number: 6683-19-8
No toxic effects have been observed in studies with soil living
With an average maximum diameter of 25.5 Å (see IUCLID Chapter 5.3.1) ,
a molecular weight of 1180 g/mol and a log Kow of > 19.6 (according to
ClogP3 and EPIwin calculations) the substance is considered to be not
bioavailable and uptake of the substance in cells via membrane
permeation of terrestrial organisms is unlikely. Especially for
terrestrial organisms whose main exposure route to contaminants is pore
water such as plants and microorganisms, uptake is not probable because
of the high adsorption potential and poor water solubility of the
substance. Due to the oral uptake of soil earthworms are the most
suitable test organisms to determine the toxicity to soil organisms.
effects on earthworm reproduction was investigated according to OECD
guideline 222, with Eisenia fetida as test species[2019 ]. Up to the
highest test concentration of 1000 mg/kg/dw (nominal) no adverse effects
on biomass, reproduction, food consumption and morphology was observed.
Hence, it can be concluded that the test substance is not harmful to
No adverse effects in the solubility range were observed in acute and
chronic aquatic toxicity studies and no hazard identified. Based on the
available ecotoxicity data and the limited bioavailability due to the
molecular size, no hazard is identified for soil organisms.
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