Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Abiotic and biotic degradation

No experimental data on hydrolysis is available. However, the substance has ester bonds which might slowly hydrolyse.

According to the experimental results on the biodegradability the substance is not readily biodegradable but can be partially eliminated in a sewage treatment plant. The prediction from Catalogic supports this results with a BOD of 2%. The predicted primary half-life of the substance was 6.03 days and the ultimate half-life 2y 11m 11d. It is assumed that the parent compound undergoes a certain degree of primary degradation, i.e. primarily ester hydrolysis resulting in the formation of benzenepropanoic acid (metilox acid, CAS 20170 -32 -5) as major degradation product. Further degradation products were identified with Catalogic.

Based on the available experimental and modelled data it cannot be confirmed whether the parent compound fulfills the persistence criteria or not, but as a worst case it is assumed that it is persistent in the environment with half lives in fresh water >40d. This assumption seems reasonable regarding the high molecular weight of the compound and the resulting limitations due to mass-transfer. It can be assumed that the relevant degradation products (quantity >0.1% mol/mol parent and logKow>=4) are not readily biodegradable and fulfill the criteria for persistence according to REACH Annex XIII as worst case.


In a weight of evidence approach considering molecular weight, molecular size, log Pow and QSAR data the bioaccumulation potential of the substance was assessed. Taking these data into account CAS 6683-19-5 cannot be regarded as bioaccumulative. Its BCF value is assumed to be clearly below 2000.

QSAR data on the relevant degradation products (quantity >0.1% mol/mol parent and logKow>=4) determined with Catalogic, show that these degradation products have a low bioaccumulation potential and are not considered to be bioaccumulative or very bioaccumulative.

Transport and distribution

Adsorption to the soil and sediment phase is expected. Distribution to air and water compartments is not probable due to the low volatility and low water solubility.

Additional information