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EC number: 476-160-4
CAS number: 54807-34-0
Table 1. Results for maternal effects
100 mg/kg bw/d
300 mg/kg bw/d
1000 mg/kg bw/d
Number of dams examined
Mortality of dams (%)
Body weight gain (mean (g))
Days 15-21 (post treatment)
Days 0 -21 (gestation)
Food consumption (mean (g))
Day 0 to 6 (pre-treatment)
Day 6 to 15 (treatment)
Day 15 to 21 (post treatment)
Table 2. Results for teratogenic effects:
litter response (Caesarean section data)
0 mg/kg bw/d
Corpora lutea (mean)
Early Resorptions (mean)
Late Resorptions (mean)
Live fetuses (%)
Dead fetuses (%)
pre-implantation loss (state %)
fetus weight (mean) [g]
Fetal sex ratio [% male fetuses]
Table 3: Examination of the fetuses
0 mg/kg bw/d
Soft tissue malformations*[%]
Soft tissue variations*[%]
This study has been performed on DMH (Dimethyl Hydantoin)
and has been used for read-across purposes. The
substance is not a developmental toxin as no maternal toxic effects and
no teratogenic/embryotoxic effects were observed.
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