Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Two aquatic toxicity studies were carried out on NaDMH: Short term toxicty to Daphnia and Toxicity to microorganisms.

The NaDMH study carried out on Daphnia gave a 48 hour EC50 of greater than 100 mg/L. Correspondingly the No Observed Effect Concentration was 100 mg/L. The effect of NaDMH on the respiration of activated sewage sludge gave a 3-hour EC50 of 2200 mg/L. The NOEC after 3 hours exposure was 320 mg/L.

The remaining aquatic toxicity studies were conducted on the analogue chemical DMH.

A study is available which was performed with rainbow trout according to EPA Guideline 72-1. DMH was tested at a nominal concentration of 1000 mg/L . The measured concentration of DMH was 972.2 mg/L. No mortalities occurred. The LC50 was therefore determined to be > 972.2 mg/L.

As previously stated all but two of these studies have been performed on DMH (Dimethyl Hydantoin) and have been used for read-across purposes. A summary of data for read-across of NaDMH with DMH is given in Section 13.