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EC number: 476-160-4
CAS number: 54807-34-0
Two carcinogenicity studies have been performed with DMH with both the rat and mouse. The substance is not considered to be oncogenic neither in rat nor in mice. NOAEL > 1000 mg/kg bw/day.
The substance is not considered to be oncogenic neither in rat nor in
mice. NOAEL > 1000 mg/kg bw/day. Therefore classification is not
As previously stated these studies have been performed on DMH (Dimethyl
Hydantoin) and have been used for read-across purposes. A summary of
data for read-across of NaDMH with DMH is given in Section 13.
estimation of No Observed Effect Level of DMH greater than 1000 mg/kg
bw/day was based upon the observation of no-effect in the neoplastic
histopathological data of the high dose group. The absence of effect was
due to non-statistically significant observations in the test.
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