Registration Dossier

Environmental fate & pathways

Biodegradation in water: screening tests

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

A readily biodegradability test in accordance with GLP and OECD Guideline 301 B was performed on the chemical NaDMH. NaDMH attained 85% degradation after 28 days and is therefore considered readily biodegradable.
Additionally a read-across study on the analogue chemical DMH attained 88% degradation after 28 days and this also was considered readily biodegradable.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable

Additional information

NaDMH and DMH both had studies of reliability 1 concluding that the substance was readily biodegradable. A further study on DMH was also available however this was reliability 2 and concluded that DMH wasn’t readily biodegradable. This could possibly be related to the fact that a mixture of innoculum was used rather than activated sludge alone, this would have limited the biodegradability of the substance.

As previously stated two studies have been performed on DMH (Dimethyl Hydantoin) and have been used for read-across purposes. A summary of data for read-across of NaDMH with DMH is given in Section 13.