Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 609-066-0 | CAS number: 35123-06-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
Additional information
For the terrestrial compartment four different studies representing three trophic levels are available.
Toxicity to soil macroorganisms
Two guideline terrestrial invertebrate studies are available, one acute toxicity study with the earthworm, Eisenia fetida, and one long-term study with the collembolan Folsomia candida. In the acute earthworm study (OECD 207), no mortalities were observed up to concentrations of 1000 mg/kg soil dw, therefore the NOEC was determined to be ≥1000 mg/kg soil bw. During the chronic collembolan study (OECD 232), no effect on adult survival was observed up to the highest test concentration (NOEC≥600 mg/kg soil dw). The number of juveniles was significantly reduced at concentrations of 185 mg/kg soil dw and higher, thus the NOEC for reproduction was determined to be 103 mg/kg dw and the corresponding EC10 was 195.6 mg/kg soil dw.
Toxicity to terrestrial plants
In a terrestrial plant study (OECD 208) no influence on emergence was observed resulting in an NOEC≥1000 mg/kg soil dw for all three species (Avena sativa, Brassica napus, Vicia sativa). For the endpoint of dry weight, the NOEC was determined to be 62.5 mg/kg soil dw, with Brassica napus (oilseed rape) being the most sensitive species. Effects on dry shoot length were also observed and the respective NOEC was determined to be 250 mg/kg soil dw.
Toxicity to soil microorganisms
No negative effects were detected in nitrifying microorganisms in a OECD 216 study. After 28 days the nitrate content was increased compared to controls. The NOEC was set to be <62.5 mg/kg soil dw. However since no adverse effects could be determined, the test item is considered to have no long-term adverse effects on nitrate formation in soil at concentrations up to and including 1000 mg test item/kg soil dw.
The overall NOEC for the terrestrial compartment is considered to be 62.5 mg/kg soil dw based on the terrestrial plant study (OECD 208).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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