Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 609-066-0
CAS number: 35123-06-9
n.s. not significantly different compared to control
* significantly different compared to the control
In a chronic toxicity study, the effects of 2-hydroxy-N,N-dimethylpropanamide on Folsomia candida were investigated. Juvenile Collembola were exposed for 28 days at concentrations of 9.80, 17.6, 31.8, 57.2, 103, 185, 333 and 600 mg test item/kg soil dry weight and a control, in groups of 10 animals with 4 replicates for the test item treatments and 8 replicates for the control. The test item was incorporated into artificial soil with a content of 5% peat. After 28 days, assessment of adult mortality, behavioural effects and reproduction was performed.
Mortality of the Collembola exposed to the test item (3% - 5%) was not statistically significantly different from the control mortality (3%) up to and including the highest test concentration of 600 mg test item/kg soil dry weight. Thus, the NOEC for 2-hydroxy-N,N-dimethylpropanamide based on mortality was determined to be ≥600 mg test item/kg soil dry weight. The LC50 was estimated to be >600 mg test item/kg soil dry weight.
The mean number of juveniles counted 28 days after introduction of the parental Collembola into the test vessels was 832 in the control and 868, 796, 851, 806, 777, 717, 624 and 252 at the test concentrations of 9.80, 17.6, 31.8, 57.2, 103, 185, 333 and 600 mg test item/kg soil dry weight, respectively. Reproduction of the Collembola exposed to 2-hydroxy-N,N-dimethylpropanamide was not statistically significantly different compared to the control up to and including the test concentration of 103 mg test item/kg soil dry weight. At 185 mg test item/kg soil dry weight and above, reproduction was statistically significantly reduced compared to the control. The NOEC based on reproduction was determined to be 103 mg test item/kg soil dry weight. The EC10 based on reproduction was 195.6 mg test item/kg soil dry weight.
No behavioural abnormalities were observed in any of the treatment groups.
One study of long-term toxicity to terrestrial arthropods conducted according to OECD 232 is available. The 28-day EC10 for reproduction was determined to be 195.6 mg test item/kg soil dw. The corresponding NOEC was 103 mg/kg soil dw.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again