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EC number: 609-066-0
CAS number: 35123-06-9
The test substance was investigated for its skin sensitizing potential
within an LLNA. The test item was not a sensitizer to skin.
the study the test substance was dissolved in Dimethylformamide (DMF)
and was assessed for its possible contact allergenic potential. For this
purpose a local lymph node assay was performed according to OECD 429,
adopted in 2002. The test substance was applied to the dorsum of both
mouse ears in concentrations of 25, 50, and 100 %. The animals did not
show any clinical signs during the course of the study and no cases of
mortality were observed. In this study Stimulation Indices (S.I.) of
1.6, 1.8, and 2.4 were determined with the test item at concentrations
of 25, 50, and 100 % in DMF, respectively. The test item is considered
to be "not sensitizing" to skin.
Migrated from Short description of key information:
The test substance was investigated for its skin sensitizing
potential within an LLNA. The test item was not a sensitizer to skin.
Justification for selection of skin sensitisation endpoint:
GLP and guideline compliant study.
Based on the available data, there is no
sensitisation potential of the test substance. Therefore there is no
need for classification and labeling acorrding to Directive 67/548/EEC
(DSD) and Regulation (EC) No 1272/2008 (CLP).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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