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EC number: 431-620-3
CAS number: -
Acute oral toxicity- discriminating dose
2000 mg/kg bw: No
adverse effects were observed at the highest dose.
dermal toxicity- discriminating dose 2000 mg/kg bw. No
deaths or any other adverse effects were observed at the highest dose.
Acute inhalation toxicity- discriminating
dose 5 mg/ L / 4 hr. the LC50 4hr cut-off value exceeds 12.5 mg/L.
28 day oral repeat dose toxicity: Surviving
1000 mg/kg/day males showed dark liver at terminal kill.
Females treated with 1000 mg/kg/day and
animals of either sex from the 150 or 15 mg/kg/day treatment group
showed no treatment-related macroscopic abnormalities at terminal kill.
NOAEL determined ot be 150 mg/kg bw/day.
Reproductive Toxicity Screening: No effects
were noted at the highest dose tsted (500mg/kg bw/day)- NOAEL determined
to be 500 mg/kg bw/day.
skin exposure: slight erythema was noted in guinea
pigs exposed topically during the induction pahse of the Maximisation test,
no effects were noted during the rabbit skin irritation test.
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