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EC number: 431-620-3
CAS number: 162537-11-3
Representative sampling was ensured by rolling the sample container for
approximately 10 minutes and sampling from the top, middle and bottom
prior to definitive testing.
The results of the sieving procedure (screening) are shown at the table
The cumulative amounts found for the individual particle size cut-points
for all three determinations are shown in the table below:
Particle size distribution of BMS 214702-01 was determined using a
cascade impactor. The proportion of test material having a particle size
less than 10 μm, and thus was inhalable, was 18.6%. Most of these
particles would not make it to the alveolar region. They would deposit
higher in the respiratory tract.
Proportion of test material having a particle size less than 10 μm was
Proportion of test material having a particle size less than 100 μm was
Results indicate that the proportion by mass of particles which, if
inhaled, can be expected to deposit in the respiratory tract in man is
18.6%. However, there were too few data points to allow for accurate
assessment of mass median aerodynamic diametre.
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