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EC number: 226-789-3
CAS number: 5468-75-7
combined repeated dose toxicity study with reproduction/developmental
toxicity screening test with
the test item administered by oral gavage in Wistar rats (10/sex/group)
was performed according to OECD TG 422. The dose levels for this study
50, 200 and 1000 mg/kg bw/day. Oral
dosing of male and fernale Wistar rats with the test item at dose levels
of 50, 200
or 1000 mg/kg b.w./day for at least 28 days, revealed no
treatment-related findings on parental
animals, on fertility, on embryo-foetal development, or on pup
the results presented in this report a definitive No Observed Adverse
Effect Level (NOAEL)
for parental and reproduction/developmental toxicity for the test item
mg/kg/day was established.
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