Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 226-789-3 | CAS number: 5468-75-7
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Remarks:
- test procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 005
- Report date:
- 2005
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Analytical Expert Group (ETAD)
- Version / remarks:
- method for substances with very low solubilty in both water and n-octanol
- Principles of method if other than guideline:
- Determination of solubility in n-octanol and calculation of log Pow with water solubility
- Type of method:
- estimation method (solubility ratio)
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2-methylphenyl)-3-oxobutyramide]
- EC Number:
- 226-789-3
- EC Name:
- 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2-methylphenyl)-3-oxobutyramide]
- Cas Number:
- 5468-75-7
- Molecular formula:
- C34H30Cl2N6O4
- IUPAC Name:
- 2-[(1E)-2-{3,3'-dichloro-4'-[(1E)-2-{1-[(2-methylphenyl)carbamoyl]-2-oxopropyl}diazen-1-yl]-[1,1'-biphenyl]-4-yl}diazen-1-yl]-N-(2-methylphenyl)-3-oxobutanamide
- Test material form:
- solid: nanoform
Constituent 1
Study design
- Analytical method:
- photometric method
Results and discussion
Partition coefficientopen allclose all
- Type:
- Pow
- Partition coefficient:
- 3.3
- Temp.:
- 24 °C
- pH:
- ca. 7
- Type:
- log Pow
- Partition coefficient:
- 0.5
- Temp.:
- 24 °C
- pH:
- ca. 7
- Details on results:
- Pow and log Pow were calculated from equilibrium concentrations in n-octanol (see below) and in water (see section 4.8)
Any other information on results incl. tables
The solubility in n-octanol was determined to be 2.6 µg/L at ambient temperature (24-25°C). This figure represents the mean of 5 determinations (range: 1.81 -3.59 µg/L, sigma = 0.76). The solubility in water was determined to be 0.8 µg/L (section 4.8)
These solubilities (equilibrium concentrations considering the tests performed) are used to calculate Pow with the following equation:
Pow = equilibrium concentration in octanol / equilibrium concentration in water
Pow = 2.6 µg/L / 0.8 µg/L
Pow = 3.3
log Pow = 0.5
Applicant's summary and conclusion
- Conclusions:
- The test substance has a log Pow of 0.5.
- Executive summary:
The log Pow of the test substance was calculated from the equilibrium concentrations in water and in n-octanol. The log Pow at 24-25 °C was 0.5.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
