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EC number: 265-057-8
CAS number: 64741-56-6
A complex residuum from the vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly greater than C34 and boiling above approximately 495°C (923°F).
Male and female rats were exposed by inhalation to a mixture of aerosol
and vapour derived from a bitumen fume condensate, collected from a
heated storage tank. Following periods of exposure of up to 12 months,
there was no evidence of increased micronucleus formation in bone marrow
and peripheral blood cells.
Systemic exposure to bitumen fumes was confirmed by presence of PAH
metabolites in urine, increased metabolising activity in lung, DNA
adducts in respirtatory tissue and repression of RBCcount in bone marrow.
Exposure to bitumen fumes was not genotoxic in an in-vivo micronucleus
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