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EC number: 265-057-8
CAS number: 64741-56-6
A complex residuum from the vacuum distillation of the residuum from atmospheric distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly greater than C34 and boiling above approximately 495°C (923°F).
The study investigated a small group (17) of paving workers exposed to
bitumen, which contained low level PAH and turned out not mutagenic by
Ames test. Urine was tested for mutagenicity by Ames test, D-glucaric
acid and urinary thio-esters. Mutagenic urine was higher in exposed
compared to non-exposed individuals only in the Ames test, one strain,
and after metabolic activation. Workers are co-exposed to diesel exhaust
and possibly coal tar, which limits the usefulness of the study.
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