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EC number: 260-906-9
CAS number: 57693-14-8
Test group skin response after challenge
(25 % test substance in distilled water) after 24 and 48 h
The allergenic potential of test substance
was assessed in albino guinea pigs by the maximization-test of B.
Magnusson and A.M. Kligman (1969), as per OECD guideline 406 .
Five males were used as control group and
10 males were used as test group.
The highest non-irritating test article
concentration used for challenge application was 25% in bi-distilled
All treated animals of the test group
showed erythematous skin reactions 24 and 48 hours after epidermal
challenge exposure; no reactions were seen in the negative control
Test material is judged skin sensitising.
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