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EC number: 260-906-9
CAS number: 57693-14-8
Rabbit no. & sex
IPR = 3
IPR = O+
time after treatment
E = degree of opacity
F = area of cornea involved
(E × F) × 5
(D × 5)
A = redness
B = chemosis
C = discharge
score (A+B+C)× 2
= Initial pain reaction; +
one drop of local anaesthetic instilled into both eyes 1 to 2 minutes
before treatment ; Sf = black staining of the fur around the treated eye
A single application of 0.1 ml (67 mg) of
test material was administered to the non irrigated eye of 3 rabbits.
Ocular reactions were recorded 1, 24, 48, and 72 hours and 7 days after
The test material produced scattered and
diffuse corneal opacity, iridial inflammation and moderate conjunctival
irritation. Black staining of the fur was noted around all treated eyes
throughout the study. All treated eyes appeared normal at the 7-day
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