Registration Dossier
Registration Dossier
Diss Factsheets
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EC number: 260-906-9 | CAS number: 57693-14-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Endpoint summary
Administrative data
Description of key information
LC50 (96h) on fish = 3 mg/l
EC50 (48h) on daphnia = 30.2 mg/l
ErC50 (7d) on frond number = 103 mg/l
ErC50 (7d) on dry weight = 73 mg/l
EC50 on microorganisms = 107 mg/l
Additional information
Short-term toxicity to fish
One key study and four supporting studies (OECD 203) showed nominal LC50 values between 1 and 10 mg/l. In a fifth supporting study according with DIN 38 412, LC50 = 10 – 22 mg/l. The key study was selected based on test procedure and details provided.
Long-term toxicity to fish and daphnia
Long term studies do not need to be conducted based on column 2 in Annex IX of REACH Regulation (EC 1907/2006): CSA does not indicate the need for further investigations.
Short term toxicity to daphnia
Two studies (OECD 202) were used as key studies. Both reported EC50 (48h) values between 10 and 100 mg/l.
Toxicity to aquatic plants other than algae
Test item was found to inhibit the growth of the monocotyledon Lemna minor after 7 days with the following effect values (nominal concentrations): EC50 values for growth rate inhibition of frond number (ErC50) and dry weight (ErdwC50) were 103 mg/l and 73.8 mg/l, respectively; EC50 values for yield inhibition of frond number (EyC50) and dry weight (EydwC50) were both between 10 and 100 mg/l, i.e. 22.8 mg/L and 17.6 mg/l, respectively.
Toxicity to microorganisms
Studies accoridng to OECD 209 were available. The key study reported an EC50 of 107 mg/l and a NOEC of 7.81 mg/l; the supporting study reported an EC50 of 32.6 mg/l. The value of the supporting study was not used for chemical safety assessment as no data on purity and composition was available.
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