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EC number: 260-906-9
CAS number: 57693-14-8
Two studies according to OECD guideline
406 were available. Both available studies indicate that test substance
is a strong sensitiser by inducing skin hypersensitvity in 80 to 100 %
of the treated animals, responding to an intrademal induction of 5 % in water
or physiological saline.
According to the CLP regulation (EC
1272/2008), based on a Guinea pig maximisation test, classification
in category 1A applies if:
≥ 30 % responding at ≤ 0,1 % intradermal
induction dose or ≥ 60 % responding at > 0.1 % to ≤ 1 % intradermal
and classification in category 1B applies
≥ 30 % to < 60 % responding at > 0.1 % to
≤ 1 % intradermal induction dose or ≥ 30 % responding at > 1 %
intradermal induction dose.
Based on a positive response in 80 to 100
% animals responding to an intradermal induction at 5%, classification
in category 1B applies.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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