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EC number: 265-042-6
CAS number: 64741-42-0
A complex combination of hydrocarbons produced by distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 220°C (-4°F to 428°F).
With activation, there was no trend indicating a dose-related response,
and therefore, the increase in number of mutations was not thought to be
API PS-6 (unleaded gasoline) was examined for its potential to induce
mutations in the L5178Y mouse lymphoma cell line, in both the presence
and absence of an S9 metabolic activation system. The doses were: 0.065,
0.13, 0.26, 0.52, and 1.04 microliters/ml. API PS-6 did not induce a
statistically significant increase in the number of mutant colonies at
any of the doses with or without metabolic activation; little
cytotoxicity was observed. Both the positive and negative controls
responded appropriately. Under the conditions of this study, API PS-6
was not mutagenic. This finding does not warrant classification of
unleaded gasoline as a genotoxin under Regulation (EC) 1272/2008 on
classification, labeling, and packaging of substances and mixtures (CLP)
or under the Directive 67/518/EEC for dangerous substances and Directive
1999/45/EC for preparations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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