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EC number: 265-042-6
CAS number: 64741-42-0
A complex combination of hydrocarbons produced by distillation of crude oil. It consists of hydrocarbons having carbon numbers predominantly in the range of C4 through C11 and boiling in the range of approximately minus 20°C to 220°C (-4°F to 428°F).
Male Hartley Albino guinea pigs were dermally exposed to test article
F-64-01 neat at a volume of 0.5 ml for each of three induction phases.
For the challenge phase, the test article was administered undiluted for
both the induction/challenge and challenge control group animals.
Response grades, severity and incidence at the time of the challenge
exposure for the test article F-64-01 indicated no dermal responsiveness
in the induction/challenge group above that observed in the naive
challenge control group. The naive challenge irritation control group
animals were also free of any dermal response. Response grades, severity
and incidence at the time of the challenge exposure for DNCB resulted in
a significantly higher response in the induction/challenge group than
that observed in the naive challenge control group.
Under the conditions of the test, the test article F-64-01 was not a
delayed contact sensitizer and the positive control DNCB was a delayed
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