Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-247-3
CAS number: -
The modelling results show that the uptake of hydrotropes from either a
diluted solution, or the concentrated product, into the stratum corneum,
for short exposure durations varies between 0.36% and 0.55% of the
- % dermal absorption is independent of concentration (i.e., the dermal
flux is not saturated) and skin contact area
- % dermal absorption increases with duration exposure
- for all concentrations, the 23 hour uptake efficiency is ca 2.8% for
this exposure scenario (it is unlikely if not inconceivable that anyone
would be exposed to a solution containing a hydrotrope for 23 hours
without removal and/or washing of the exposed surface; therefore the
2.8% uptake efficiency would represent an upper bound value)
- a 2.8% dermal absorption factor can therefore be used as an upper
bound value in the exposure dose calculation
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Sellel veebilehel kasutatakse küpsiseid, et tagada lehe parim kasutus.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again