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EC number: 219-941-5
CAS number: 2579-20-6
This study was conducted to assess the acute toxicity of 1,3-BAC
in female rats administered by oral gavage at the single doses of 300
mg/kg (first and second administration) and 2000 mg/kg (third
At the third administration at 2000 mg/kg, decreases in locomotor
activity, ptosis, hypothermia, and abnormalities in respiration and
posture were observed, and all animals died by Day 2. In necropsy,
abnormalities in the stomach and intestine were observed. The changes in
the stomach and intestine were considered to be attributed to irritation
caused by the test substance. In the first and second administration at
300 mg/kg, no deaths or abnormalities attributed to the test substance
were observed in the clinical signs, body weight, or necropsy findings.
Therefore, 1,3-BAC was classified into Category 4 (>300-2000 mg/kg
b.w.) in accordance with the Globally Harmonized Classification System
(GHS), under the conditions of this study.
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