Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 295-405-4
CAS number: 92045-23-3
A complex combination of hydrocarbons produced by the distillation of the products of a steam cracking process. It consists predominantly of hydrocarbons having a carbon number of C4, predominantly 1-butene and 2-butene, containing also butane and isobutene and boiling in the range of approximately minus 12°C to 5°C (10.4°F to 41°F).
no effect on the body weight of the animals and no indications of
toxicity were observed during the daily observations of the in-life
portion of the study. Statistically significant increases in the
frequencies of MN-PCE in both sexes of all groups treated with the test
material were observed as compared to the negative controls. Although
statistical analyses indicated a significant dose response, the
difference in MN-PCE incidence at the high- (20 mg/L) and low- (0.5
mg/L) dose was minimal. The positive control treatment induced a
significant increase in the frequency of MN-PCE. The mean proportion of
PCE among the erythrocytes (200/animal) in the bone marrow was not
affected following exposure to the test material while the positive
control treatment significantly reduced this value.
Butadiene (Low 1,3-Butadiene Content) was tested in a mouse bone-marrow micronucleus
assay. C3H/HeNCrlBR mice were exposed to 20mg/L (20,000 mg/m3)for 4h/day
for 2 days. A positive result was obtained.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Sellel veebilehel kasutatakse küpsiseid, et tagada lehe parim kasutus.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again