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EC number: 201-535-4
CAS number: 84-51-5
Individual and mean scores for cornea, iris and conjunctivae
Rabbit Number and Sex (Bodyweigh in kg)
Time after treatment
125 Male (2.64)
92 Female (3.12)
100 Female (3.01)
A study was performed to assess the irritancy potential of the test
material 2-ethylanthraquinone to the eye o f the New Zealand White
rabbit. The method used followed that described in the OECD TG 405.
A single application o f the test material to the non-irrigated eye of
three rabbits produced minimal to moderate conjunctival irritation.
Diffuse corneal opacity and iridial inflammation was confined to one
treated eye. All treated eyes appeared normal 72 hours after treatment
or on day 7.
The test material was classified as a mild irritant to the rabbit eye
according to a modified Kay and Calandra classification system. The test
material is classified as non-irritant to the rabbit eye according to
Regulation (EC) No 1272/2008 (CLP).
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