Registration Dossier
Registration Dossier
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EC number: 201-254-7 | CAS number: 80-15-9
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of cumene hydroperoxide to Daphnia magna was investigated in a study conducted according to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test) and EU Method C.2 under GLP conditions. The 48 h NOEC, LOEC, and EC50 were determined to be 9.15, 18.23, and 18.84 mg/L based on geometric mean measured concentrations.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 18.84 mg/L
Additional information
Short-term toxicity to aquatic invertebrates
Reliable results from studies conducted according to guideline and or conducted according or similar to a national standard method are available.
The acute toxicity of cumene hydroperoxide to Daphnia magna was investigated in a study conducted according to OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test) and EU Method C.2 under GLP conditions. The stability of the test substance was investigated via HPLC/UV-VIS. The 48 h NOEC, LOEC, and EC50 were determined to be 9.15, 18.23, and 18.84 mg/L based on geometric mean measured concentrations.
In two studies conducted according or similar to the German DIN 38412, Part 11 (draft), 24 h EC50 values in the range between 6 and 7 mg/L nominal were determined.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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