Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-805-4
CAS number: 99-97-8
Acute oral toxicity study was
conducted for the test chemical as per OECD 401. The test chemical was
dosed via gavage to groups of five male and five female
Sprague-Dawley rats at the test concentration of 1250, 1800 and 2500
mg/kg bw. The rats were observed for 14 days after test chemical
administration for mortality and clinical signs. Mortality occurred on
days 2 to 3 in 1/5, 5/5, and 5/5 male rats and in 1/5, 0/5, and 5/5
female rats dosed at 1250, 1800, and 2500 mg/kg, respectively. Decreased
activity (slight to moderate) was observed up to test day 9 in 7 rats
dosed at 1250 mg/kg, in 6 rats dosed at 1800 mg/kg, and in 8 rats dosed
at 2500 mg/kg. Decreased activity (extreme) was observed up to test day
2 in 2 rats dosed at 1250 mg/kg and in 3 rats dosed at 2500
mg/kg. Hunched posture was observed on test days 5-8 in one rat dosed at
1800 mg/kg. Salivation (slight to moderate) was observed the day after
dosing in one rat dosed at 2500 mg/kg.Under the conditions of the study,
the acute oral toxicity dose (LD50) value was considered to be 1300
mg/kg in male rats, 1950 mg/kg in female rats and 1650 mg/kg in male and
female rats combined.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again