Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Bioaccumulation: aquatic / sediment

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
bioaccumulation in aquatic species: fish
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data is from authoritative databases
Justification for type of information:
Data is from authoritative databases
Qualifier:
according to guideline
Guideline:
other: as mentioned below
Principles of method if other than guideline:
Environmental bioconcentration factor of the test chemical in fish was estimated using a log Kow and a regression-derived equation.
GLP compliance:
not specified
Radiolabelling:
not specified
Vehicle:
not specified
Test organisms (species):
other: Fish
Route of exposure:
aqueous
Test type:
not specified
Water / sediment media type:
natural water: freshwater
Reference substance (positive control):
not specified
Details on estimation of bioconcentration:
BASIS FOR CALCULATION OF BCF
- Result based on calculated log Kow of: 2.81
Key result
Type:
BCF
Value:
33 dimensionless
Basis:
whole body w.w.
Calculation basis:
other: BCF value of test chemical was estimated using a logKow and a regression-derived equation.
Remarks on result:
other: Other details not known
Validity criteria fulfilled:
not specified
Conclusions:
The estimated BCF (bioaccumulation factor) of test chemical was determined to be 33 dimensionless.
Executive summary:

The bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation BCF value was calculated using a log Kow of 2.81 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 33 dimensionless, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical was considered to be non-accumulative in aquatic organisms.

Description of key information

The bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation BCF value was calculated using a log Kow of 2.81 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 33 dimensionless, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical was considered to be non-accumulative in aquatic organisms.

Key value for chemical safety assessment

BCF (aquatic species):
33 dimensionless

Additional information

Data from various sources for the test chemical were reviewed for the bioaccumulation end point which are summarized as below:

The bioaccumulation study in fish was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation BCF value was calculated using a log Kow of 2.81 and a regression-derived equation. The estimated BCF (bioaccumulation factor) value of test chemical was determined to be 33 dimensionless, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical was considered to be non-accumulative in aquatic organisms.

Above data further supported by the data obtained from secondary source. The bioaccumulation study on aquatic organisms was conducted for estimating the BCF (bioaccumulation factor) value of test chemical. The bioaccumulation factor (BCF) value was calculated using a log Kow of 2.81 and an equation. The estimated BCF value of the test chemical was determined to be 29.09 dimensionless, which does not exceed the bioconcentration threshold of 2000, indicating that the test chemical was considered to be non-bioaccumulative in aquatic organisms.

Similar BCFBAF model of Estimation Programs Interface was used to predict the bioconcentration factor (BCF value) of the test chemical. The bioconcentration factor (BCF) of test chemical was estimated to be 33.19 L/kg whole body w.w (at 25 °C) which does not exceed the bio concentration threshold of 2000, indicating that the test chemical was not expected to bioaccumulate in the food chain.

On the basis of above results for test chemical, it can be concluded that the BCF value of test chemical was ranges from 29.09 to 33.19,which does not exceeds the bioconcentration threshold of 2000, indicating that the test chemical was not expected to bioaccumulate in the food chain.