Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 200-854-6
CAS number: 75-25-2
The acute oral toxicity of the test
substance to Sprague-Daawley rats. No guideline was followed but the
study used a method similar to the classical LD50 test.
To establish the dose levels to be used
groups of two animals were administered test compounds at 250-3000 mg/kg
and the mortality data were recorded and used ot det dosew in the main
test. For the main test five doses between 546 and 2100
mg/kg were employed and 10 males and 10 females used at each dose level.
Dosing solutions were administered to animals in corn oil using
premature infant feeding tubes (8 Fr., 15 in. length) at a maximum
volume of 2ml/kg. Clinical observations were made for 14 days after
dosing and a post-mortem examination was performed on animals which died
during this period. All surviving animals were killed at the end of 14
days and subjected to gross pathologic examination.
The acute oral LD50 of the test substance in
Sprague-Dawley rats was 1388 and 1147 mg/kg bw in males and females
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Tato webová stránka používá cookies, aby se vám naše stránky používaly co nejlépe.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again