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EC number: 200-854-6
CAS number: 75-25-2
An expert review of toxicokinetic data on
Bromoformv was undertaken to provide a basic toxicokinetic asessment as
required for REACH Annex VIII registration. The assessment was based on
available data from toxicological studies studies and some literature
references. No specific toxicokinetic studies were undertaken.
Observations from an acute oral study and
repeated dose oral toxicity studies demonstrate that Bromoform can be
rapidly absorbed from the gastrointestinal system. It is also
anticipated that an inhaled dose will be rapidly absorbed across lung
Systemically absorbed Bromoform can be
expected to be excreted rapidly via exhalation either as parent
compound, or as CO2 derived from metabolic breakdown.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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