Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

In the Key study entitled " Dimethyl Isophthalate:  Acute Toxicity to the Rainbow Trout, Oncorhynchus mykiss, Determined Under Static-Renewal Test 
Conditions" (Romine ABC, 2013)  the estimated 96 hour LC50 value was 21.6 mg/L, with 95% confidence limits of 14.9 - 32.4 mg/L.  The 96 hour 
NOEC was determined to be 6.3 mg/L, based on a lack of mortality and sublethal effects at the lowest test substance concentration.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
21.6 mg/L

Additional information

Vertellus Performance Materials, Inc. contracted ABC Laboratories, Inc. to conduct a 96-hour static-renewal toxicity test with rainbow trout exposed to dimethyl isophthalate. The criterion for effect was mortality, defined as lack of gill movement and no response to physical stimulus. Based on nominal concentrations, the estimated 96‑hour LC50value was 21.6 mg/L, with 95% confidence limits of 14.9 mg/L and 32.4 mg/L. The 96‑hour NOEC was determined to be 6.3 mg /L, based on a lack of mortality and sublethal effects at the lowest test substance concentration.