Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 215-951-9 | CAS number: 1459-93-4
Endpoint summary
Administrative data
Description of key information
Experimental studies indicate that the substance is not a skin irritant but is an eye irritant
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (irritating)
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
No skin irritation was observed in rabbits treated with DMIP using a semiocclusive patch exposure. In a guideline eye irritation study, the flaked material resulted in eye irritation to the conjunctiva only, which resolved within 48 hours.
Justification for selection of skin irritation / corrosion endpoint:
experimental result conducted by guideline and GLP
Justification for selection of eye irritation endpoint:
experimental result conducted by guideline and GLP
Effects on eye irritation: irritating
Justification for classification or non-classification
Experimental evidence in rabbits indicates that the substance is not a skin irritant or corrosive , but is an eye irritant. The substance is classified as an eye irritant, Category 2, according to Regulation EC No. 1272/2008.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
