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EC number: 426-040-2 | CAS number: 25713-60-4 SR-245
Biodegradation in water and sediment: simulation tests
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Link to relevant study record(s)
Description of key information
14C-FR-245 Aerobic Transformation in Aquatic Sediment Systems
14C-FR-245 Anaerobic Transformation in Aquatic Sediment Systems
Key value for chemical safety assessment
Additional information
Aerobic and anaerobic transformation of14C radioactive labeled sample of FR-245 in aquatic sediment systems was studied. The studies were performed in two systems, River system and in Pond system.
Degradation of FR-245 in total aerobic and anaerobic aquatic systems was shown to occur at a very slow rate. No radioactivity was found in the water phase following the direct application of14C-FR-245 to the sediment.
The materials detected in the study are not product of biological degradation in a natural water/sediment system. It is an impurity present in the test item and may be a result of hydrolysis or auto-radiolysis. It can’t also not be excluded that it represents an artifact/impurity from the radio-synthesis.
For the aerobic aquatic system, DT50 values of 472 and 592 days were calculated for the river and pond sediment, respectively. For the anaerobic aquatic system, DT50 values of 252 and 462 days were calculated for the river and pond sediment, respectively.
The criterion for a substance to be very persistence (vP) is DT50>180d. In both studies DT50 values are above the criterion value. Thus, the studies indicate that FR-245 is very persistent - vP.
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