Registration Dossier
Registration Dossier
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EC number: 426-040-2 | CAS number: 25713-60-4 SR-245
Endpoint summary
Administrative data
Description of key information
Acute skin irritation to the rabbit
Acute Eye irritation to the rabbit
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
Acute irritation studies were performed on the skin and eye of rabbits.
Skin irritation/corrosion: No skin irritation was caused by 4 hours exposure to FR-245.
Eye irritation: Instillation of FR-245 resulted in irritation of the conjunctivae, which consisted of redness and/or chemosis. The irritation had completely resolved within 48 hours in all animals.
Effect level: empty Endpoint conclusion: Adverse effect observed
Justification for classification or non-classification
Based on the experimental results of the Acute skin and eye irritation studies and according to the EEC criteria for classification and labelling requirements for dangerous substances and preparations (Guidelines in Commission Directive 93/21/EEC, 27th April 1993), FR-245 does not have to be classified for skin or eye irritation and has no obligatory labelling requirement for skin irritation or eye irritation.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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