Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 230-638-7 | CAS number: 7237-83-4
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Acute Toxicity of tris(oxiranylmethyl)benzene-1,2,4-tricarboxylate to Daphnia magna in a Semi-Static 48-hour Immobilisation Test according to OECD 202 and Commission Regulation (EC) No 440/2008, C.2.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 21.7 mg/L
Additional information
The acute Toxicity of tris(oxiranylmethyl)benzene-1,2,4-tricarboxylate to Daphnia magna was determined in a semi static 48-hour immobilisation test. The test was conducted in accordance with OECD Guideline 202 and the Commission Regulation (EC) No 440/2008. This study encompassed 6 treatment groups (5 test item concentrations at nominal 100, 45.5, 20.7, 9.4 and 4.3 mg test item/L and one control) each containing 20 individuals. The immobility of the Daphnia was determined by visual observation after 24 and 48 hours of test duration.The samples collected at test start and after 48 hours were analysed via HPLC method. After 24 hours in the control and in the concentrations of nominal 4.3 and 45.5 mg test item/L no immobilisation of the test animals was observed. At nominal 9.4 and 20.7 mg test item/L, one animal was immobile. At the highest test concentration of nominal 100 mg/L 10 Daphnia were immobile after 24 hours test duration. At the end of the test the toxicity of the test item to Daphnia magna had increased. After 48 hours of exposure one immobile animal was observed in the control. In the lowest test concentration of nominal 4.3 mg/L no immobility was observed. At the concentration of nominal 9.4 mg/L, 4 animals were immobile and 10 animals were immobile at the concentration of nominal 20.7 and 45.5 mg/L. At the highest test item concentration of nominal 100 mg/L all daphnids were dead after 48 h of exposure. The 48-hour NOEC was determined to be 3.74 mg test item/L. The 48-hour LOEC was determined to be 7.86 mg test item/L The 48-hour EC50value was calculated to be 21.7 mg test item/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
