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EC number: 204-278-6 | CAS number: 118-79-6
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Toxicity to terrestrial arthropods
Administrative data
Link to relevant study record(s)
Description of key information
Geuijen (2001) was considered adequate and reliable for use in assessing the toxicity of 2,4,6-tribromophenol in terrestrial arthropods. The study was performed to both OECD guideline 213 and 214, the study was also GLP compliant.
Key value for chemical safety assessment
Additional information
Reference: Geuijen, W.H.C. (2001)
Reliability: 1
Results: Some mortality was observed in the contact test with tribromophenol in the honey bee (<10%), however, this was less than the level of mortality observed in the solvent control. Mean Abbott corrected cumulative mortality was 0% at all doses. Contact LD50 was concluded to be above 100 ug/bee. The NOEC was set at the highest tested dosage, i.e. 100 ug/bee.
Dosing orally, tribromophenol induced some mortality (<10%). At the highest tested dosage (actual dosage 112 ug/bee) mortality was 7% after 48 hours. There was no mortality in the solvent control. Hence, the oral LD50 for Tribromophenol is above 112 ug/bee. The NOEC was set at the highest tested dosage, i.e. 112 ug/bee.
Duration |
Endpoint |
Effect conc. |
Nominal/Measured |
Conc. based on |
Basis for effect |
Remarks (e.g. 95% CL) |
96 h |
NOEC |
100 µg per animal |
nominal |
test mat. |
mortality |
Contact test |
96 h |
LC50 |
> 100 µg per animal |
nominal |
test mat. |
mortality |
Contact test |
48 h |
NOEC |
112 µg per animal |
nominal |
test mat. |
mortality |
Oral |
48 h |
LD50 |
> 112 µg per animal |
nominal |
test mat. |
mortality |
Oral test |
The following information is taken into account for effects on soil arthropods for the derivation of PNEC:
Geuijen (2001) was considered adequate and reliable for use in assessing the toxicity of 2,4,6-tribromophenol in terrestrial arthropods. The study was performed to both OECD guideline 213 and 214, the study was also GLP compliant.
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