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Physical & Chemical properties

Partition coefficient

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Description of key information

QSAR prediction: logKow>14
Analogue substance of lower molecular weight: logKow>12

Key value for chemical safety assessment

at the temperature of:
20 °C

Additional information

In a test to measure the partition co-efficient, the logPow of a lower molecular weight surrogate substance was estimated to be greater than 12. QSAR modelling using the substance Durasyn 124 predicts the logPow to be greater than 14. Such high values suggest the likelihood of low bioavailability.