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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
calculation (if not (Q)SAR)
Adequacy of study:
key study
Study period:
November 22, 1 994 - November 28, 1994
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
other: EU method A.8 (estimation based on individual solubilities in n-octanol and water)
Version / remarks:
1992
Deviations:
no
GLP compliance:
yes
Type of method:
estimation method (solubility ratio)
Partition coefficient type:
octanol-water
Type:
log Pow
Partition coefficient:
<= -0.55
Temp.:
25 °C
Remarks on result:
other: pH not specified

solubility in water: >/= 270 g/L

solubility in n-octanol = 76.9 g/L

Kow = 76.9/270000 = 2.85E-04

log Kow </= -0.55

Conclusions:
The log Kow of Reaction product of lauryl-PDA/lauryl-DETA with chloroacetic acid based on its individual solubilities in n-octanol (76.9 g/L) and water (>/=270 g/L) is
Executive summary:

Reaction product of lauryl-PDA/lauryl-DETA with chloroacetic acid is an amphoteric surfactant. The methods described in the Test Guideline A.8 are not applicable to surface-active materials. An estimate of the partition coefficient n-octanol/water is made based on the individual solubilities in n-octanol and water:

solubility in water: >/= 270 g/L

solubility in n-octanol = 76.9 g/L

The log Kow of Reaction product of lauryl-PDA/lauryl-DETA with chloroacetic acid was determined to be </=-0.55 at 25°C.

Description of key information

</=-0.55 at 25°C (individual solubilities in n-octanol and water; RL1; GLP)

Key value for chemical safety assessment

Log Kow (Log Pow):
-0.55
at the temperature of:
25 °C

Additional information

Reaction product of lauryl-PDA/lauryl-DETA with chloroacetic acid is an amphoteric surfactant. The methods described in the Test Guideline A.8 are not applicable to surface-active materials. An estimate of the partition coefficient n-octanol/water is made based on the individual solubilities in n-octanol and water:

solubility in water: >/= 270 g/L

solubility in n-octanol = 76.9 g/L

The log Kow of Reaction product of lauryl-PDA/lauryl-DETA with chloroacetic acid was determined to be </=-0.55 at 25°C.