Registration Dossier

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
40.6 µg/L
Assessment factor:
3
Extrapolation method:
sensitivity distribution

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
40.6 µg/L
Assessment factor:
3
Extrapolation method:
sensitivity distribution

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
51.6 mg/L
Assessment factor:
10
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
PNEC sediment (freshwater)
PNEC value:
5 051 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Sediment (marine water)

Hazard assessment conclusion:
PNEC sediment (marine water)
PNEC value:
5 051 mg/kg sediment dw
Extrapolation method:
equilibrium partitioning method

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
PNEC soil
PNEC value:
7.3 mg/kg soil dw
Assessment factor:
10
Extrapolation method:
assessment factor

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
insufficient hazard data available (further information necessary)

Additional information

Under neutral "real-life" water conditions (i.e. between pH 6 -8), Indium trichloride, precipitates and forms In(OH)3 complexes. Therefore no clear dose-response was found between ecotoxicity endpoints and dissolved Indium concentrations. All results were expressed as total indium concentrations.

Conclusion on classification

acute (short-term) aquatic hazard

The lowest EC50 observed in the acute aquatic ecotoxicity database covering the 3 main taxonomic groups (unicellular algae, invertebrates, fish) is 1.6 mg In/L on the unicellular algae Pseudokircherniella subcapitata. This EC50 value is related to the concentration of the In-ion. It is concluded that In-substances are not classified for acute aquatic hazard under CLP.

long-term aquatic hazard

The lowest NOEC/EC10 value observed in the chronic aquatic ecotoxicity database covering the 3 main taxonomic groups (unicellular algae, invertebrates, fish) is 94 µg In/L on the invertebrate Ceriodaphnia dubia. This value is related to the concentration of the In-ion. The InCl3 loading required to get this In-concentration is 94 µg/l * 221.13 (MW InCl3) / 114.76 (MW In) = 181 µg/L.

For long-term aquatic classification, it needs to be decided whether or not the substance is raîdly degradable in the water column. However, the concept of degradability does not apply to inorganic substances. Since the aim of this parameter is to assess whether or not the substance remains long enough in the water column to be able to exert a long-term effect, the concept of "rapid removal from the water column" has been proposed to assess this characteristic for metal substances. As such, rapid removal from the water column is considered as equivalent to "rapid degradability".

The data on the transformation/dissolution test demonstrate that indium substances completely and very rapidly dissappear out of the water column under environmentally relevant conditions of pH (Section 5, for TD data on the substance see Section 4.8.). The In-substances are consequently considered to behave equivalently to "rapidly degradable" organic substances.

Taking into account that i) there are adequate chronic toxicity data avalailable on the substance, ii) that the substance can be considered as equivalent to being rapidly degradable, and iii) that the lowest observed NOEC/EC10 value for InCl3 is 181µg/l, the substance is classified as category chronic 3 for long-term aquatic hazard under CLP.