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Diss Factsheets

Physical & Chemical properties

Solubility in organic solvents / fat solubility

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Description of key information

Solubility in 3 % acetic acid and 10 % ethanol lower than 0.07 mg/l at 20 °C

Key value for chemical safety assessment

Additional information

The determination of the solubility of test item in 3 % acetic acid and 10 % ethanol, respectively, was pertormed according to the EEC Directive 92/69, A.6 "Water Solubility" (1992) and the OECD guideline No. 105, "Water Solubility" (adopted July 27 , 1995), using the column elution method.

During the main tests of each solvent six samples have been analysed in the first run (0.52 l/min) and six samples during the second run (0.26 l/min), each with a sampling interval of one hour. Total elution time was 104 hours for both solvents. The sample measurement was performed by HPLC. The test item could not be detected in any of the eluate samples. Therefore, the solubility of test item in 3 % acetic acid and 10 % ethanol, respectively, at 20 °C, was determined to be below the smallest point of calibration, which is lower than 0.07 mg/l, using the column elution method.